What is xenical 120 mg used for

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24 hours in XENICAL and placebo treatment groups, respectively. Patients should be strongly encouraged to take a multivitamin supplement that contains fat-soluble vitamins to ensure adequate nutrition because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene .

XENICAL should not be used after the given expiration date. Buying drugs in your country requires a prescription. View larger picture color dark blue shape oblong imprint this information has been compiled for use by healthcare practitioners and consumers in the united states xenical 120, roche back. Cyclosporine should be administered 3 hours after the administration of XENICAL .

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Doses above 120 mg three times a day have not been shown to provide additional benefit. If XENICAL is taken with any one meal very high in fat, the possibility of gastrointestinal effects increases. Statistical significance based on intent-to-treat population, last observation carried forward. In addition, all patients were placed on a behavior modification program and offered exercise counseling. Discover what you’ll experience at G.

It is used by certain overweight people,. In clinical trials in obese diabetic patients, hypoglycemia and abdominal distension were also observed. The diet utilized during year 1 was a reduced-calorie diet. All studies, with the exception of 14 161, were conducted at centers specialized in treating obesity and complications of obesity. Buying drugs in your country requires a prescription. Table 4 illustrates the percentage of adult patients on XENICAL and placebo who developed a low vitamin level on two or more consecutive visits during 1 and 2 years of therapy in studies in which patients were not previously receiving vitamin supplementation.

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The relative changes in risk factors associated with obesity following 2 years of therapy were also assessed in the population as a whole and the population with abnormal risk factors at randomization. XENICAL inhibited absorption of a vitamin E acetate supplement. In the 4-year XENDOS study, the general pattern of adverse events was similar to that reported for the 1- and 2-year studies with the total incidence of gastrointestinal-related adverse events occurring in year 1 decreasing each year over the 4-year period.

Ethanol does not affect orlistat’s effect on preventing the absorption of fat. HDL ratio, triglycerides, fasting glucose, fasting insulin, diastolic blood pressure, waist circumference, and hip circumference. It is not known if XENICAL is safe and effective in children under 12 years old. At the end of the study, the mean percent weight loss in the placebo group was -2.

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The iron balance was decreased by 64. This Patient Information leaflet summarizes the most important information about XENICAL. Pediatric Use Safety and effectiveness in pediatric patients below the age of 12 have not been established. Buying drugs in your country requires a prescription.

Patients treated concomitantly with XENICAL and levothyroxine should be monitored for changes in thyroid function. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to XENICAL exposure. For more information, ask your doctor or pharmacist. In addition, all patients were offered nutritional counseling. Orlistat is used for the treatment of obesity. Based on patients with a baseline and at least one follow-up OGTT measurement, ITT LOCF study population.

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Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. 1 kg in body weight after a year,. For patients receiving both XENICAL and levothyroxine therapy, administer levothyroxine and XENICAL at least 4 hours apart. Do not take XENICAL if you are pregnant or plan to become pregnant. Patients should also be advised to take multivitamin supplementation at least two hours before or after the administration of XENICAL, or at bedtime .

This Patient Information has been approved by the U. Digoxin In 12 normal-weight subjects receiving XENICAL 120 mg three times a day for 6 days, XENICAL did not alter the pharmacokinetics of a single dose of digoxin. A reduced therapeutic effect of amiodarone is possible. The relative changes in risk factors associated with obesity following 1 year of therapy with XENICAL and placebo are presented for the population as a whole and for the population with abnormal values at randomization. 4 lbs in the patients treated with XENICAL and 5.

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Cases of oxalate nephrolithiasis and oxalate nephropathy with renal failure have been reported. The effect of commencing orlistat treatment in patients on stable amiodarone therapy has not been studied. Specific Populations No pharmacokinetic study was conducted for specific populations such as geriatric, different races, and patients with renal and hepatic impairment.

Anticoagulants Including Warfarin Vitamin K absorption may be decreased with XENICAL. Pharmacokinetics Absorption Systemic exposure to orlistat is minimal. Rare cases of leukocytoclastic vasculitis have been reported.

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The effect of XENICAL to delay the onset of type 2 diabetes in obese patients with IGT is presumably due to weight loss, and not to any independent effects of the drug on glucose or insulin metabolism. Patients taking 120 mg half an hr antecedent to feminine xenical three times a day had an average fall of 6. However, GI adverse events may occur in some individuals over a period of 6 months or longer. The safety and efficacy of XENICAL have been evaluated in obese adolescent patients aged 12 to 16 years.

The daily intake of fat, carbohydrate, and protein should be distributed over three main meals. Following one year of treatment, BMI decreased by an average of 0. Fat-soluble Vitamin Supplements And Analogues Data from a pharmacokinetic interaction study showed that the absorption of beta-carotene supplement is reduced when concomitantly administered with XENICAL.

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In patients found to have an impaired OGTT at randomization, the percent of patients improving to normal or deteriorating to diabetic status following 1 and 2 years of treatment with XENICAL compared to placebo are presented. Your doctor may do certain tests to check your kidney function during treatment with XENICAL. XENICAL and cyclosporine should not be simultaneously coadministered. BMI and body weight after 52 weeks of treatment for the intent-to-treat population are presented in Table 12. Inactive Ingredients : microcrystalline cellulose, sodium starch glycolate, sodium lauryl sulfate, povidone, talc, gelatin and titanium dioxide.

The vaccine is carefully evaluated by fda scientists and doctors xenical should not be used by anyone age 12 to 18 without the advice of a doctor. These are not all the possible side effects of XENICAL. It is not known if XENICAL passes into your breast milk. Rare cases of hypersensitivity have been reported with the use of XENICAL.

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Because XENICAL has been shown to reduce the absorption of some fat-soluble vitamins and betacarotene, patients should be counseled to take a multivitamin containing fat-soluble vitamins to ensure adequate nutrition . The diet utilized during year 2 was designed for weight maintenance and not weight loss. HOW SUPPLIED Dosage Forms And Strengths XENICAL 120 mg turquoise capsules imprinted with ROCHE and XENICAL 120 in black ink.

INDICATIONS XENICAL is indicated for obesity management including weight loss and weight maintenance when used in conjunction with a reduced-calorie diet. Keep XENICAL and all medicines out of the reach of children. In several studies of up to 6-weeks duration, the effects of therapeutic doses of XENICAL on gastrointestinal and systemic physiological processes were assessed in normal weight and obese subjects.

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For XENICAL, the most common adverse events resulting in discontinuation of treatment were gastrointestinal. The capsule is imprinted with black. Phenytoin In 12 normal-weight subjects receiving XENICAL 120 mg three times a day for 7 days, XENICAL did not alter the pharmacokinetics of a single 300-mg dose of phenytoin.

Orlistat and its M1 and M3 metabolites were also subject to biliary excretion. Buying drugs in your country requires a prescription. 1 year in five large multicenter studies for the intent-to-treat populations are presented in Table 6. Rare cases of increase in transaminases and in alkaline phosphatase and hepatitis that may be serious have been reported.