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1 year in five large multicenter studies for the intent-to-treat populations are presented in Table 6. The diet utilized during year 2 was designed for weight maintenance and not weight loss. DRUG INTERACTIONS Cyclosporine Data from a XENICAL and cyclosporine drug interaction study indicate a reduction in cyclosporine plasma levels when XENICAL was coadministered with cyclosporine. Digoxin In 12 normal-weight subjects receiving XENICAL 120 mg three times a day for 6 days, XENICAL did not alter the pharmacokinetics of a single dose of digoxin.
XENICAL is a turquoise, hard-gelatin capsule containing pellets of powder. In clinical trials in obese diabetic patients, hypoglycemia and abdominal distension were also observed. Discontinuation Of Treatment In controlled clinical trials, 8.
For patients receiving both XENICAL and levothyroxine therapy, administer levothyroxine and XENICAL at least 4 hours apart. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. However, GI adverse events may occur in some individuals over a period of 6 months or longer. BMI and body weight after 52 weeks of treatment for the intent-to-treat population are presented in Table 12.
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For example, a person who weighs 180 lbs and is 5’5″ has a BMI of 30. When combined with increased physical activity and a low-cal diet, Generic Xenical could work wonders to help people lose weight. For patients receiving both XENICAL and cyclosporine therapy, administer cyclosporine 3 hours after XENICAL.
Patients should be advised to adhere to dietary guidelines . Although we will do our best to protect your personal data, we cannot guarantee the security of your data transmitted to our site. It is necessary to reduce and maintain weight with the help of Generic Xenical. The number where these two meet is your BMI. An oral dose of Sibutramine capsules is meant to consume via the oral administration. HDL ratio, triglycerides, fasting glucose, fasting insulin, diastolic blood pressure, waist circumference, and hip circumference.
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Please refer to the patient information leaflet for more information on Orlistat. Your doctor may do certain tests to check your kidney function during treatment with XENICAL. Read this Patient Information before you start taking XENICAL and each time you get a refill. Postmarketing Experience The following adverse reactions have been identified during postapproval use of XENICAL. Oral Contraceptives In 20 normal-weight female subjects, the treatment of XENICAL 120 mg three times a day for 23 days resulted in no changes in the ovulation-suppressing action of oral contraceptives.
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They may not work as well while you take XENICAL. This helps to reduce the fat absorbed by the body. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The capsule is imprinted with black. Patients should not take XENICAL if they are pregnant, have chronic malabsorption syndrome, cholestasis or hypersensitivity to XENICAL or to any component of this product . This list is not complete and other drugs may interact with orlistat.
Take a multivitamin containing vitamins A, D, E, K, and beta-carotene one time each day. In such circumstances, we reserve the right to charge you a reasonable fee in dealing with such requests, or alternatively, we may refuse to comply with your request in these circumstances. If you take too much XENICAL call your doctor or go to the nearest hospital emergency room right away. Its use should be accompanied by healthy diet and exercise, with the weight being monitored closely.
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If you have a meal containing a very high proportion of fat, the possibility of gastrointestinal side effects when taking Orlistat will be increased. Silva, Coffeyville I could play baseball due to my excessive weight, but with the help of Generic Xenical losing weight was fast and so simple, now I can play baseball with the same energy. Increases In Urinary Oxalate Some patients may develop increased levels of urinary oxalate following treatment with XENICAL. This helps us to provide you with a good experience when you browse our site and also allows us to improve our site.
A reduced therapeutic effect of amiodarone is possible. We have put in place procedures to deal with any suspected personal data breach and will notify you and any applicable regulator of a breach where we are legally required to do so. How do you rate this product?
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Pravastatin In a 2-way crossover study of 24 normal-weight, mildly hypercholesterolemic patients receiving XENICAL 120 mg three times a day for 6 days, XENICAL did not affect the pharmacokinetics of pravastatin. NOTE: Users taking this medicine may or may not experience the above-mentioned side effects or any other side effects. Population With Abnormal Risk Factors at Randomization The relative differences in risk factors between treatment with XENICAL and placebo were similar to the results following 1 year of therapy for LDL- and HDL-cholesterol, triglycerides, fasting insulin, diastolic blood pressure, and waist circumference. If you take a levothyroxine medicine, take XENICAL and levothyroxine at least 4 hours apart.
Read the label of all food items you consume, paying special attention to the number of servings per container. Upon discontinuation of therapy, fecal fat content usually returns to pretreatment levels within 48 to 72 hours. If you would like more information, talk with your doctor. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
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XENICAL should not be used after the given expiration date. Helps to reduce the risk of certain health conditions: Besides weight loss, Generic Xenical also prevents obese people from certain risk factors such as high blood pressure, diabetes, and triglycerides. In the 4-year XENDOS study, the general pattern of adverse events was similar to that reported for the 1- and 2-year studies with the total incidence of gastrointestinal-related adverse events occurring in year 1 decreasing each year over the 4-year period.
Take your vitamin or supplement at bedtime, or at least 2 hours before or after you take orlistat. European Commission which give personal data the same protection it has in Europe. Available for Android and iOS devices. For XENICAL, the most common adverse events resulting in discontinuation of treatment were gastrointestinal. Weight loss is not recommended during pregnancy, even if you are overweight or obese.
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Orlistat should be taken with water immediately before, during or up to one hour after a main meal. XENICAL and other medicines may affect each other causing side effects. Amiodarone A pharmacokinetic study, where amiodarone was orally administered during orlistat treatment, demonstrated a reduction in exposure to amiodarone and its metabolite, desethylamiodarone . We are responsible for transactions placed on our site and deploy a Comodo SSL certificate so that all data is transferred securely using SSL. They are the natural effects of orlistat’s fat-blocking action and are actually signs that the medication is working properly.
Based on fecal fat measurements, the effect of XENICAL is seen as soon as 24 to 48 hours after dosing. If you skip a meal or you eat a meal that does not contain any fat, skip your orlistat dose for that meal. There may be other treatments available for your condition which you can read about on our site or discuss with your GP or our team. You can calculate your BMI here. US, we may transfer data to them if they are part of the Privacy Shield framework, which requires them to provide similar protection to personal data shared between the Europe and the US.
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24,000 prescription drugs, over-the-counter medicines and natural products. Acute oxalate nephropathy after treatment with XENICAL has been reported in patients with or at risk for renal disease . Whilst using Orlistat patients should make a diet plan where calorie intake is divided over 3 main meals. Do not start a new medication without telling your doctor.
XENICAL patients had a normal oral glucose tolerance test while 10. You may report side effects to FDA at 1-800-FDA-1088. This medication comes with patient instructions for safe and effective use.
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Rare cases of hypersensitivity have been reported with the use of XENICAL. SIDE EFFECTS Clinical Trials Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in patients. Tell your doctor about all medications you use. Ethanol does not affect orlistat’s effect on preventing the absorption of fat. Each capsule contains a pellet formulation consisting of 120 mg of the active ingredient, orlistat, as well as the inactive ingredients microcrystalline cellulose, sodium starch glycolate, sodium lauryl sulfate, povidone, and talc.
What are the ingredients in XENICAL? XENICAL is available for oral administration as a turquoise hard-gelatin capsule. This Patient Information leaflet summarizes the most important information about XENICAL.